NMN and CoQ10 are among the most popular supplements in the U.S. However, it may take 4 to 12 weeks to see any change. In one analysis, after reviewing 12 clinical studies, researchers concluded that CoQ10 has the potential to lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by 10 mm Hg, without significant side effects. reversing side-effects of "statin" drugs, and preventing migraine headaches. As for Policosanols a number of studies carried out on Cuban patients have indeed shown that that not only does policosanol reduce cholesterol, it does so more effectively than the statin drugs. ... Furthermore, unlike the statins, policosanol, at least in the Cuban studies, increases HDL, the so-called good cholesterol. New research suggests that NMN may restore cellular metabolism, and have profound anti-aging effects. Occurring naturally in the body, NMN (Î²-Nicotinamide mononucleotide) is critical for the conversion of nutrients into energy. Supplementing NMN as part of your daily regime could offer energy revitalization, protection from the aging process, and decreased risk of cardiovascular complications.